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Welcome to the UTMB Research Resources Blog

Sponsored by Research Services, the blog is set up to assist the UTMB research community by disseminating information from various sources in one reliable, relatable and easy to locate place.  Users will be able to find updates from NIH, UT System and UTMB as well as special events and lectures taking place at the University, Galveston and in the area. Available funding opportunities are also included and in most cases broken down by career level for convenience and searching ease.

The blog is designed to be an interactive tool for researchers at all levels.  Readers are encouraged to comment, suggest topics and forward ideas.

The blog can be delivered directly to your email by following these simple instructions.

GrantsWatch

Since April 2017

PI Dept Title Sponsor Total All Years
Bourne, Nigel Pediatric Vaccinology HSV testing in animal models Conrad (federal flow through from US Agency for International Development)  $           57,711
Freiberg, Alexander Niclas Pathology Arenavirus entry inhibitors Arisan Therapeutics Corporation  $           14,320
Garcia-Blanco, Mariano Biochemistry & Molecular Biology Consequences and Mechanism of Aberrant Splicing in African American Prostate Cancer George Washington University (federal flow through from NCI)  $         352,625
Geisbert, Thomas W Microbiology And Immunology Mechanisms of Evasion of the Innate and Adaptive Immune Responses to Filoviruses Georgia State University (federal flow through from NIAID)  $         503,122
Geisbert, Thomas W Microbiology And Immunology Preclinical Development of Human Monoclonal Antibodies for Postexposure Treatment of Crimean-Congo Hemorrhagic Fever National Inst of Allergy & Infectious Diseases  $      6,014,180
Hughes, Grant Pathology Portable, high-surety detection of Zika virus directly in mosquitoes and humans Paratus Diagnostics  $             7,750
Khan, M Firoze Pathology Trichloroethene Exposure and Autoimmune Hepatitis National Inst of Environmental Health Sciences  $      1,743,750
Kramer, George C Anesthesiology TraumaCath Preliminary Study TheraNova, LLC (federal flow through from DTRA)  $           22,379
Liu, Hua Ophthalmology cAMP/EPAC1 pathway in retinal neuronal damage after ischemic injury American Heart Association-National  $         231,000
Makino, Shinji Microbiology And Immunology Rational Development of a Novel Attenuated Rift Valley Fever Virus Vaccine National Inst of Allergy & Infectious Diseases  $         426,250
McGrath, Christine OB/Gyn Adol Research Impact of ART Adherence and Early Infant HIV Diagnosis on the Effectiveness of Option B+ in Kenya University of Washington (federal flow through from CDC)  $           25,124
McGrath, Christine OB/Gyn Adol Research Assessment of adolescents HIV care in large HIV Treatment Programs in Kenya University of Washington (federal flow through from CDC)  $             9,749
McGrath, Christine OB/Gyn Adol Research Prevalence, Cofactors, and Types of Family Planning Methods Used by HIV-infected Women in HIV Care Programs in Kenya University of Washington (federal flow through from CDC)  $             9,749
Motin, Vladimir Pathology Research collaborator services to Collaborative Biological Engagement Program CH2M HILL Inc (federal flow through from Defense Threat Reduction Agency)  $           69,868
Paessler, Slobodan Pathology Elucidation of mechanisms of pathogenicity stability and immunogenicity of novel live attenuated vaccine against Bolivian Hemorrhagic Fever and its applications Japan Society for the Promotion of Science  $         101,200
Patel, Pooja Rani OB/GYN – GYN Research An intervention to increase LARC use in adolescent females National Inst of Child Health & Human Development  $         472,296
Rajarathnam, Krishna Biochemistry & Molecular Biology Malvern MicroCal PEAQ Isothermal Titration Calorimeter Office of The Director – Natl Inst Hlth  $         120,350
Rodriguez, Ana M OB/GYN – GYN Research Improving Cervical Cancer Screening and Prevention in the Lower Rio Grande Valley Through Public Outreach, Patient Navigation and Telementoring University of Texas M D Anderson Cancer (flow through from CPRIT)  $        151,565
Temple, Jeffrey R Ob/Gyn – Behav Health & Rsrch Preventing Teen Dating and Youth Violence by Addressing Shared Risk and Protective Factors City of Houston (federal flow through from CDC)  $          90,883
Thangamani, Saravanan Pathology Tick Determinants of Powassan Virus Transmission National Inst of Allergy & Infectious Diseases  $     1,921,000
Torres, Alfredo Microbiology And Immunology Defining Correlates of Production of a Broad-spectrum Attenuated Burkholderia Vaccine Defense Threat Reduction Agency  $     1,547,264
Tseng, Chien-Te K Microbiology And Immunology Evaluation of Adenovirus- based MERS Vaccines in vivo King Abdulaziz University  $          77,000
Wang, Tian Microbiology And Immunology Revolutionary Eilat-based Chikungunya Vaccine Vector National Inst of Allergy & Infectious Diseases  $     2,939,058
Wong, Rebeca PMCH-Administration Health of Older Minorities National Inst on Aging  $             886,860
Yu,  Xiaoying PMCH-Administration Improving prevention of mother-to-child HIV transmission outcomes in Malawi Baylor College of Medicine (flow through from Fogarty International Center)  $                 5,357
Zhou,  Jia Pharmacology Drug Discovery of Bax Activators for the Treatment of Breast Cancer Department of Defense  $             744,938

GCC Updates

News from the Gulf Coast Consortia

A Collaboration of Baylor College of Medicine, Rice University, University of Houston, University of Texas Health Science Center, University of Texas Medical Branch at Galveston, University of Texas MD Anderson Cancer Center, and Institute of Biosciences & Technology of Texas A&M Health Science Center

www.gulfcoastconsortia.org

Congratulations

The NIH-funded, multi-institutional National Library of Medicine (NLM) Training Program in Biomedical Informatics (T15LM007093, Program Director Dr. Lydia Kavraki, Rice University) welcomes new PhD student Scott Malec, whose fellowship begins on July 1. Scott and his mentors Elmer Bernstam and Trevor Cohen are all at the School of Biomedical Informatics, UT Health Science Center at Houston.

 

UPCOMING GCC EVENTS

Mike Hogg Antimicrobial Resistance Research Seminar Series, July 13

Kevin W. Gary, Pharm.D., M.S., FASHP, UH College of Pharmacy, presents “Which Antibiotics Cause C. difficile Infection?” The seminar will take place in the Bioscience Research Collaborative (BRC) Room 1003, and a networking reception will follow.  4:30-6:30. All welcome, but please register as space is limited.  For more information, contact Suzanne Tomlinson.

Save the date: Metabolism in Cancer, September 21

The featured speaker will be Prof. William G. Kaelin, Dana-Farber Cancer Institute, Harvard Medical School, and  winner of 2016 Lasker Award for basic medical research. Four perspective speakers will highlight different aspects of the field: Ronald DePinho, MDACC; Giulio Draetta, MDACC; Meng Weng, BCM; and  Deborah Johnson, BCM. Also planned are several short talks from local researchers working in the general area of metabolism research applied to cancer systems. Supported by a John S. Dunn Foundation Collaborative Research Event Award, this event will be September 21,  Onstead Auditorium, Mitchell Basic Science Research Building. For more information, contact Suzanne Tomlinson.

Save the dates for two Neuro-focused conferences, October 26 and 27:

  • GCC Cluster for Neuroengineering Conference, October 26

Confirmed speakers include Eva Dyer, Georgia Institute of Technology; Robert Greenberg, Second Sight; and Charles Lieber, Harvard University.

  • Keck Center Annual Research Conference and Poster Session, October 27

Theme: Neuroscience.  Confirmed speakers are  Eve Marder, Brandeis University, and Dan Yamins, Stanford University. Co-organizers are Carmen Dessauer, UTHealth, and Ted Wensel, BCM.

GCC Job Board

Check out the new jobs posted recently. This job board provides an opportunity for job seekers and employers to learn more about each other. Job seekers may post their resumes.  Employers (GCC Recruiter) may post their job openings. GCC Job Board

VIICTR

Learn more about GCC’s and other TMC institutions’ core facilities and equipment on the VIICTR website (Search Core Facilities).  VIICTR = Virtually Integrated Institutions for Clinical and Translational Research.

 

OTHER AREA EVENTS

July Events:

HMRI, Sankar Mitra, Houston Methodist Research Institute, DNA Damage and Repair Symposium, July 7

August Events:

RU, Advances in Tissue Engineering, August 9-12

RU, Chemical & Biomolecular Engineering Seminar, Vivek Sharma, August 31

 

 

CPRIT Announces Three new RFA’s

 

CPRIT’s grant application system is now open for three RFAs for the Academic Research program. Complete RFAs and instructions detailing applicable deadlines and requirements are available in the Funding Opportunities section of CPRIT’s website.


Recruitment of First-Time, Tenure-Track Faculty Members

Instructions for Applicants

Supports very promising emerging investigators, pursuing their first faculty appointment in Texas, who have the ability to make outstanding contributions to the field of cancer research. 

Award: Up to $2 million over a period of four years.


Recruitment of Rising Stars

Instructions for Applicants

Recruits outstanding early-stage investigators to Texas, who have demonstrated the promise for continued and enhanced contributions to the field of cancer research.

Award: Up to $4 million over a period of five years.


Recruitment of Established Investigators

Instructions for Applicants

Recruits outstanding senior research faculty with distinguished professional careers and established cancer research programs to academic institutions in Texas.

Award: Up to $6 million over a period of five years.

The application period is June 21, 2017 through June 20, 2018. Proposals must be submitted through CPRIT’s online grant application system.

Burroughs Wellcome Fund’s Investigators in the Pathogenesis of Infectious Disease

Burroughs Wellcome Fund’s Investigators in the Pathogenesis of Infectious Disease
Pre-proposals deadline:  July 14, 2017
Request for Proposals 

 

The Burroughs Wellcome Fund is now accepting pre-proposals for the Investigators in the Pathogenesis of Infectious Disease (PATH) award.  This award provides $500,000 over five years to support accomplished investigators at the assistant professor level to study pathogenesis, with a focus on the interplay between human and microbial biology, shedding light on how human and micro

bial systems are affected by their encounters.

Details

The Investigators in the Pathogenesis of Infectious Disease program provides opportunities for assistant professors to bring multidisciplinary approaches to the study of human infectious diseases. The goal of the program is to provide opportunities for accomplished investigators still early in their careers to study what happens at the points where the systems of humans and potentially infectious agents connect. The program supports research that sheds light on the fundamentals that affect the outcomes of these encounters: how colonization, infection, commensalism, and other relationships play out at levels ranging from molecular interactions to systemic ones.
PATH is a highly competitive award program that provides $500,000 over a period of five years to assistant professors. The awards are intended to give recipients the freedom and flexibility to pursue new avenues of inquiry, stimulating higher risk research projects that hold potential for significantly advancing understanding of how infectious diseases work and how health is maintained.

Eligibility

The competition will employ a two-stage process. After review of pre-proposals, full proposal invitations will be sent by October 2, 2017.

All applicants will be required to complete a web-based questionnaire assessing their eligibility to apply for this award. If eligibility criteria are met, applicants will be automatically directed to the web-based pre-proposal application.

It is strongly recommended that potential applicants review the Request for Pre-proposals before accessing the eligibility questionnaire.

Questions

BWF staff will hold a final conference call for applicants who have questions about the program:

 

Dates:  June 26, 2017

Time: 3:00 p.m. Eastern Daylight Time
Dial in number for all calls: 800-247-5110
Passcode for all calls:  BWF

 

View the Frequently Asked Questions page. If your question is not answered after reviewing the FAQs, email vmcgovern@bwfund.org with “2018 PATH” as the subject line.

 

 BWF PATH RFP Pre proposal.pdf

Ideation Challenge: Good Questions Meet Big Data

Ideation Challenge: Good Questions Meet Big Data

Up to $10,000 in Prizes

DEADLINE: July 13, 2017 11:59PM

Harvard Catalyst | The Harvard Clinical and Translational Science Center and the Crowd Innovation Laboratory at Harvard Business School invite you to participate in a new ideation challenge.

Challenge: Can you identify a human health problem that might be resolved with big data and a computational solution? Are you working on a problem that could benefit from new algorithmic solutions or improvements? Are you aware of a dataset that could be used to solve this problem or generate further ideas for solutions?

The problem must fall into the clinical and translational research realm. Topics covered might include diagnostics, therapeutics, public health, technology, or outcomes.
Examples:

·         Applying human genomic data to solve a scientific challenge

·         Using epidemiologic or other data to address a public health issue

·         Using image analysis to resolve a diagnostic or therapeutic issue

·         Using data available on a government website to resolve a new question

Eligibility: Open to the public.

Process: View the website for more details, and to submit your problem.

Deadline: July 13, 2017 at 11:59pm

Multiple prizes between $500 and $1500 will be awarded, up to $10,000 in total.

View FAQs

Email us

Note: You will not be asked to submit a dataset. You will be asked only to briefly define (in three pages or less) a problem that could benefit from a computational answer and characterize the data. In characterizing the data, consider how it might be used for a future ideation challenge related to your question topic. Data can be from your own research or from other private or public sources. This crowd sourcing opportunity is intended to help identify new opportunities as well as difficult “bottleneck” problems that create significant roadblocks to progress in healthcare, translational science, and technological innovation. 

The goal of generating these submissions is to provide a basis for developing opportunities that will continue to address important questions through cross-CTSA or local challenges in the near future.

Note: This email is intended to be disseminated to researchers, collaborators, partners, and affiliate institutions of the CTSA Program. Please post to your website and social media, share in your newsletters, and forward this email, through July 13, 2017. Please reply to this email with any questions.

 

About Harvard Catalyst

Founded in 2008, Harvard Catalyst | The Harvard Clinical and Translational Science Center is dedicated to improving human health by enabling collaboration and providing tools, training, and technologies to clinical and translational investigators. Funded by the NIH and affiliated institutions, Harvard Catalyst is a shared enterprise of Harvard University, and its resources are made available to all Harvard faculty and trainees, regardless of institutional affiliation or academic degree.

Harvard Catalyst is funded by the National Institutes of Health (NIH) Clinical and Translational Science Awards (CTSA) Program (grant UL1TR001102).

 

CDMRP Updates

The following opportunities are NOW OPEN from the Congressionally Directed Medical Research Programs (CDMRP) through the Department of Defense (DoD).

FY17 Psychological Health/Traumatic Brain Injury Research Program

Traumatic Brain Injury Data Analysis Award

Pre-Application: June 30, 2017
Application: July 30, 2017


FY 17 Multiple Sclerosis Research Program

Investigator Initiated Research Award

Pre-Application: June 26, 2017
Application: October 5, 2017

Exploration – Hypothesis Development Award

Pre-Application: June 26, 2017
Application: October 5, 2017

Did You Know? NIH Paylines and Success Rates Garner Most hits on RS Blog

Since the initiation of the UTMB Research Resources Blog, exactly three years ago, the item that has been looked at most is the NIH Paylines and Success Rates page. Since October 1, 2016, the Paylines Link has had almost 4500 views.  NIH just updated paylines on May 23, 2017 and the following are those updates:

INSTITUTE SUCCESS RATE FY2016 PAYLINE (2016) PAYLINE (2017) FURTHER INFORMATION. (CLICK LINK FOR INSTITUTE’S CURRENT FUNDING STRATEGY)
FIC 29.5 Payline not published-anticipates 10-25% success rate/FY2017 Continuing Resolution Funding Strategy
NCATS 27.7 Payline not published/FY2017 Continuing Resolution
NCCIH 13.9 FY 2017 Funding Strategy  (Continuing Resolution)
NCI 12 10 12 for New & Early Stage-Investigators. 2016 funding plan 
NEI 25.7 25% anticipated award rate. Payline not published/FY2017 Fiscal Policy  
NHGRI 25.6 Does not establish Paylines/FY2016 Funding Strategy
NHLBI 24.2 14 15 25 for Early Stage Investigators/ FY 2017 Funding Strategy (CR)
NIA 22.8 11****  FY 2016 Funding Strategy  (under 500K: 19-new investigators; 21-early stage investigators)****Significantly higher paylines for applications focusing on Alzheimer’s Disease. Follow link for details.
NIAAA 18.8  Does not establish overall Paylines/ FY 2016 Financial Management Plan 
NIAID 24 10 11 Payline for FY2017 (Funding Strategy) 15 payline for new & early-stage investigators.
NIAMS 16 13 10  Continuous Resolution Funding Strategy for 2017 (new investigators: 18)
NIBIB 14.6 14 (New Investigators: up to 28) /FY 2016 Funding Strategy  
NICHD 13.2 10 FY 2017 Funding Strategy-interim
NIDA 15.4 Payline not published/FY2016 Funding Strategy
NIDCD 26.7 Payline not published/ FY2016 Funding Strategy 
NIDCR 19.9 Payline not published/ FY2017 Funding Strategy
NIDDK 20.1 13 FY2017 Interim Funding Strategy
NIEHS 14.2 10  2016 Funding Strategy
NIGMS 29.6 Payline not published/ FY2017  Funding Strategy (Continuing Resolution)
NIMH 22.9 10-20 10-20 FY2017 Funding Strategy     (25 for new and ESI)
NIMHD 19.3 FY2016 Funding Strategy
NINDS 19.8 15 FY2017 Funding Strategy  (anticipates a success rate of 20%)
NINR 9 Payline not published/not updated

NIH Changes Path on Early/Mid Career Initiative

 

 

After receiving a hostile response from across the country about a proposed grant cap called the Grant Support Index (GSI), first reported in this blog on May 4, 2017, NIH Director Francis S. Collins, M.D. and the NIH Advisory Council have decided to drop the controversial plan.  Citing emerging themes of possible unintentional adverse consequences and deleterious effects on collaborative research to confusion about how the cap would affect researchers with Training Grants and facing resignations from long-time Committee members, the NIH decided yesterday to replace the plan with what is being called the Next Generation Researchers Initiative.

The new initiative will create a special fund — drawn from its existing budget — for early- and mid-career scientists in an attempt to lower the average age of the researchers it supports. The multi-faceted approach will also help stabilize scientists’ career paths. The new plan calls for the following:

  • Extending the payline for early stage investigators, with an aim of funding most applications that score in the top 25 percent
  • Providing additional support for mid-career investigators with ≤ 10 years as a principal investigator
    • Extending the payline for those about to lose all NIH funding
    • Identifying “rising stars” who are seeking support for their second RPG, but just missed the payline
  • Providing targeted funds in each IC by rearranging priorities in other categories estimated at:
    • ~$210 million the first year
    • Ramping up over 5 years to reach approximately $1.1 billion per year

The NIH will place more reliance on current funding programs such as:

  • NIH Common Fund’s New Innovator Awards
  • National Institute of General Medicine Sciences Maximizing Investigators’ Research Award (MIRA)
  • National Institute of Dental and Craniofacial Research Sustaining Outstanding Achievement in Research (SOAR) awards
  • National Institute of Arthritis and Musculoskeletal and Skin Diseases Supplements to Advance Research (STAR) from Projects to Programs
  • Other special awards from specific institutes

In an effort to insure the success of this initiative, the NIH will track the impact of NIH Institute and Center funding decisions for early-stage and mid-career investigators with fundable scores.  The agency will also continue to encourage the development and testing of metrics that can be used to assess the impact of NIH grant support on scientific progress.

GCC Update

News from the Gulf Coast Consortia

A Collaboration of Baylor College of Medicine, Rice University, University of Houston, University of Texas Health Science Center, University of Texas Medical Branch at Galveston, University of Texas MD Anderson Cancer Center, and Institute of Biosciences & Technology of Texas A&M Health Science Center

www.gulfcoastconsortia.org

UPCOMING GCC EVENTS:

Rigor and Reproducibility Workshop, June 9

This interactive workshop, with organizers and/or discussion facilitators from all GCC institutions, will cover topics including Experimental Design (basic science, population science, and big data science, cell assays, antibodies, human, and computational studies, etc.), Analysis and Statistics, Data Management, and Publication and Reporting. The workshop will take place from 9 am – 5 pm at the Bioscience Research Collaborative Auditorium.  Students and postdocs are encouraged to attend, and all are welcome. A certificate of completion will be provided. Registration is full. Email Dawn Koob to be placed on the waitlist. For more information, contact Suzanne Tomlinson.

Research Mentor Training Workshop for Postdocs, June 15

These popular workshops are designed to develop skills and insight in mentoring young scientists and to provide the opportunity for interactions between mentors at different institutions and in different disciplines. Time:  10:00 am – 3:00 pm; lunch will be provided.  Location: BioScience Research Collaborative, Event Hall, 6500 Main Street. Registration is full. Email Dawn Koob to be placed on the waitlist.

Antimicrobial Resistance and Gut Health, June 16

This symposium will focus on multi-drug resistant GI pathogens, especially C. difficile, mechanisms of antibiotic action on these pathogens, environmental contamination as a cause of human infectious disease, emerging methods for the rapid detection of antimicrobial resistance in patient specimens, and pharmacodynamic effects of antimicrobials on antibacterial resistance development.  Speakers include Ferric Fang, University of Washington; A. Murat Eren, University of Chicago, Soňa Peková, KitGen, Prague, Czech Republic, Tor Savidge, BCM/TCH Jennifer Auchtung, BCM; Clifford Stephan, IBT; Tony Haag, BCM; Kevin Garey, UH; and Edward Septimus, HCA/TAMU. This event will take place at the Bioscience Research Collaborative auditorium.  To register (deadline June 13th), please visit the  Symposium website. For more information, contact Suzanne Tomlinson.

Save the date: Metabolism in Cancer, September 21

The featured speaker will be Prof. William G. Kaelin, Dana-Farber Cancer Institute, Harvard Medical School, and  winner of 2016 Lasker Award for basic medical research. Four perspective speakers will highlight different aspects of the field: Ronald DePinho, MDACC; Giulio Draetta, MDACC; Meng Weng, BCM; and Deborah Johnson, BCM. Also planned are several short talks from local researchers working in the general area of metabolism research applied to cancer systems. Supported by a John S. Dunn Foundation Collaborative Research Event Award, this event will be September 21,  Onstead Auditorium, Mitchell Basic Science Research Building. For more information, contact Suzanne Tomlinson.

Save the date: Neuroengineering and Neuroscience Conferences, October 26 and 27

GCC Cluster for Neuroengineering Annual Conference, October 26; Keck Center Annual Research Conference, Theme: Neuroscience, October 27.  More information will be available soon.

President Trump keeps Collins as NIH Director

On Tuesday, President Donald Trump announced that he is keeping Francis S. Collins as director of the National Institutes of Health.  First nominated for the position in 2009 by President Obama, Trump announced that Collins would stay on in an interim role almost immediately after taking office. Many scientists have been concerned if Collins would be offered the position or would accept it on a permanent basis in the new administration.

Collins, described as a giant in the world of science after having led the Human Genome Project which produced a finished sequence of the human DNA instruction book, said, “I am grateful for the President’s vote of confidence in my ability to continue to lead this great agency.”

Despite opposition from some Republicans and proposed NIH budget cuts, members of Congress from both sides of the aisle have stated approval and excitement at the announcement.

“This is good news for the country and one of President Trump’s best appointments,” Senate health committee chairman Lamar Alexander of Tennessee said in a statement. “There’s nobody better qualified than Francis Collins to help accelerate the medical miracles that have the potential to help virtually every American family.”

Rep. Rosa DeLauro (Conn.), the ranking Democrat on the House appropriations health subcommittee, literally jumped up and down in excitement when told that the administration had decided to retain Collins.

“I’m alive because of biomedical research,” said DeLauro, a breast cancer survivor. “The discoveries that they’re making and the direction that they’re moving in — nothing is as important as what we do there because it’s about saving lives. Francis Collins gets it, he’s there, he’s an outstanding scientist and outstanding leader.”