Fungal Drug Forces HIV Suicide

Drs. Norbert Herzog & David Niesel

Drs. Norbert Herzog & David Niesel

Medical Discovery News

What do nail fungus and HIV have in common? As it turns out, the same drug may cure them both. A topical drug called Ciclopirox, commonly prescribed to treat nail fungus, has been found to kill HIV-infected cells in the lab.

The drugs that are currently used to treat HIV and prevent the progression to AIDS unfortunately do not eliminate the virus from the body. If people stop taking the drugs, the virus will rapidly take control. That means HIV-infected people have to stay on a combination of anti-retroviral drugs for the rest of their lives. Current combination drug therapies are very successful in controlling the virus and have made HIV a survivable disease. But many of the current HIV therapeutics have significant side effects including diarrhea, nausea, vomiting and even damage to the liver and kidneys. They are also expensive: about $10,000 to $12,000 per patient per year in the United States. It has long been a dream to find drugs that could eliminate the virus and cure HIV patients.

HIV is one member of a family of viruses called lentiviruses. When these viruses infect someone, they enter host cells by binding to specific receptors on their surfaces. Once inside the cell, the virus’s genetic information is converted into DNA, the same type of molecule that human genes are made of. The virus has an enzyme that inserts its genetic information into the genomes of the human cells. From that moment, that cell is infected for life. Then the virus replicates and infects other cells. Continue reading

Are you ready to start a healthier second life?

Dr. Victor Sierpina

Dr. Victor Sierpina

If I were to tell you that up to 70 percent of all visits to a doctor are now thought to have a predominantly a single cause, what might you guess? Infections? Genetics? Drug-seeking behavior? Heart disease? Cancer? Diabetes? Pain?

As Maxwell Smart, the wise-cracking detective in the old TV series “Get Smart,” used to say, “would you believe …” lifestyle factors contribute to or cause the vast majority of illness requiring medical attention?

In fact, there is even a new field of medicine named Lifestyle Medicine. I just joined the society and am planning to attend an upcoming conference where I hope to learn more about this area.

I hope to learn how better to help my patients work on lifestyle contributors to their health, wellness and illness.

Any longtime readers of this column know that my topics about health often involve things you can do yourself.

How you eat, exercise, manage stress and so forth are major factors in wellness or illness.

During the weekend, I did a unique presentation called “Second Life on Lifestyle Medicine.” Continue reading

Mental health as important as physical health in children

Drs. Sally Robinson & Keith Bly

Drs. Sally Robinson & Keith Bly

Keeping Kids Healthy

Hissy fits. Temper tantrums. The blues. Like adults, children also suffer from these conditions from time to time.

But what if it has become an insurmountable problem for your child? When should you seek help for your child? A frank discussion with your pediatrician is a good place to begin understanding the seriousness of your child’s problem.

According to the Surgeon General at the U.S. Department of Health and Human Services, “In the United States, 1 in 10 children and adolescents suffer from mental illness severe enough to cause some level of impairment.

“Yet, in any given year, it is estimated that less than 1 in 5 of these children identified as having a significant mental illness receives needed treatment. The long-term consequences of untreated childhood disorders are costly, in both human and fiscal terms.”

Unfortunately, there is a serious stigma that is placed on people with mental health issues. Because of this stigma, emotional, developmental and behavioral needs cause much suffering in children. Continue reading

The Tomb of an Egyptian Doctor

Drs. Norbert Herzog & David Niesel

Drs. Norbert Herzog & David Niesel

Medical Discovery News

It’s not every day that archeologists uncover the tomb of an Egyptian pharaoh. But on one special day they discovered not the tomb of a pharaoh but the physician to them. Abusir, the great royal cemetery south of Cairo, is the final resting place of Shepseskaf-Ankh, head physician of Upper and Lower Egypt during the Fifth Dynasty of the Old Kingdom.

This tomb was dated to about 2400 B.C. By this time, the famous pyramids of Giza had already been constructed, so rulers of the Fifth Dynasty built pyramids farther south between 2465 and 2325 B.C. This is the third tomb of a physician discovered so far. They were entombed along with other court officials and high-level priests close to the rulers they served in life, and would continue to do so in death, according to Egyptian beliefs of the afterlife.

Shepseskaf-Ankh was from an elite Egyptian family and also held the title of priest, which was carved on the door of the tomb. It is a relatively large tomb, another indicator of his importance, with an open court and eight burial chambers for him and his family. Continue reading

Women: Care for your heart, know your risks

Dr. Rafic Berbarie

Dr. Rafic Berbarie

“I’m worried about my risk of having a heart attack.”

Whenever I start my office notes in seeing patients, the first line I fill out is the patient’s chief complaint. The above statement is a common complaint in my general cardiology practice. But often the patients have no symptoms; rather, a friend or loved one just had a heart attack and so they are worried and want a heart “checkup.”

February is heart disease awareness in women month, and as a physician, I want you to know what can be done to help prevent heart attacks.

While awareness is growing, people are often shocked to hear that heart disease is the No. 1 killer of women in the United States. In fact, if you added up how many women died of cancer, the number still would not equal the number of women dying from heart disease.

And while there are established screening guidelines for several cancers, there are no unifying screening guidelines for heart disease in women.

My first recommendation is to have a good primary care doctor who is reviewing your risk factors for heart disease. Continue reading

Testosterone plays role in obesity for men

Dr. Victor Sierpina

Dr. Victor Sierpina

Men, there is now a simple medical biomarker at-home test for you called CYCYP.

Look straight down and see if you can see your … mmm, anatomy. If not, likely you are suffering from visceral or belly fat, or maybe you have a vision problem.

For many years, we guys have thought of the obesity issue as something that mainly troubled the fairer sex.

It seems it has always been culturally appropriate for the ladies to be concerned about their shapely figures and how to stay attractive for us guys.

We men rarely, if ever, seem to be concerned or even discuss such matters outside of the gym.

However, the surprising news is that obesity or overweight rates for men are at 72 percent and rising, and for women it is 64 percent and stable.

Men also have a higher risk of cancer, diabetes and heart disease with a life expectancy of 76 years compared to 81 for women. Continue reading

Do We Smell the Same Thing?

Medical Discovery News

Have you ever wondered if we all sense the world in the same way? Evidence suggests that the sense of smell is highly individualized, based on genetic differences. This could revolutionize scents and food flavors into custom-designed creations for individuals.

Humans have specialized neuronal cells within the lining the nasal cavities, part of what’s called the olfactory epithelium. The surface of these cells, like much of the nasal cavity, is covered with mucus. Odor molecules dissolve into this layer and are detected when they bind to receptors on the neurons. This sets off a string of biochemical events that produces a signal, which travels along the olfactory nerve to the olfactory bulb of the brain. Then that signal is transferred to different regions of the brain’s cerebrum. Here odors can be distinguished and characterized. These signals are stored in long-term memory, which is linked to emotional memory. That’s why particular smells can evoke memories. This process is quite complex due to the highly evolved sense of smell in humans. Continue reading

Serve healthier drinking alternatives over sweetened soft drinks

Drs. Sally Robinson & Keith Bly

Drs. Sally Robinson & Keith Bly

Keeping Kids Healthy

All of us need to think about ways to encourage healthy lifestyles for your family.

Almost 25 percent of children in the U.S. are overweight.

Lately, there has been a lot of discussion about soft drinks in schools and how they contribute to the increasing obesity problem in the U.S. Some legislators have even suggested a “sin” tax on high-fructose foods and drinks.

In an effort to control the growing number of children becoming overweight, the American Academy of Pediatrics is urging school officials to remove soft drinks from vending machines in schools and replace them with healthier drinks, such as milk, 100 percent fruit juice or water.

Other suggestions for limiting access to sodas while children are in school include turning off vending machines during regular school hours and placing the machines in out-of-the-way places, so they are not as noticeable. Continue reading

Statewide event to help get you moving

Drs. Victor & Michelle Sierpina

Drs. Victor & Michelle Sierpina

Where in the heck did January go? Were you one of the 83 percent of Americans who made New Year’s resolutions that have already fallen by the wayside before this month is out?

Did you vow to improve your health, to live a more healthful lifestyle, to eat more nutritiously, lose weight and get more exercise?

Maybe a gym membership seems beyond your budget, the chilly weather prevented those outdoor activities you planned, and you haven’t found a way to jump-start your exercise regime.

Here is a foolproof, no excuses opportunity to get back on track for your own good health.

It is free. It is accessible to everyone. It is independent of weather. It … is walking.

Luckily in Galveston you can walk indoors regardless of weather conditions at places like the Galveston Island Community Center, 4700 Broadway, and a few other locations as well. Continue reading

The relationship between sweat and sleep

Drs. Norbert Herzog & David Niesel

Drs. Norbert Herzog & David Niesel

Medical Discovery News

If only getting to sleep were really as easy as counting sheep. More than half of Americans admit to struggling with insomnia a few nights a week.

And the loss of sleep doesn’t just make a person tired, it can affect how long they live. People who average six or fewer hours of sleep each night had higher mortality rates than those who slept seven or more. New research has provided more insight into how people can overcome or prevent insomnia.

Problems falling asleep initially, waking up during the night and then having problems getting back to sleep, feeling tired upon waking in the morning, and waking up before the alarm all count as insomnia — it’s both the ability to fall asleep and stay asleep.

There are two different types: primary (a direct issue with sleep) and secondary (sleep issues caused by an underlying medical condition such as depression, asthma and overuse of alcohol).

Insomnia can lead to other serious medical issues including memory problems, depression and heart disease as well as car accidents. Continue reading